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Autophagy in Cancer Promotes Therapeutic Resistance Autophagy is a highly regulated process by which long-lived proteins, organelles, and protein aggregates are captured within autophagosomes, which are then fused with lysosomes for degradation.1 Auto...

Keywords: Apoptosis, Autophagy, Cancer, Degradations, Metabolites, transformation Discover Bioactive Small Molecules for Gene Regulation The loss of regulation of gene expression is a key component to many human disease states, including neurodegenerative disorders, autoimmune conditions and, most prominently, cancers. Keywords: Acetylations, Epigenetics, Gene expression, Genomics, Methylations, Post translational modifications, Transcription Histone Modification and Chromatin Remodeling Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure.

The primary protein components of chromatin are the his...

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